Beirne B. Carter Immunology Center
Department of Microbiology, Immunology, and Cancer Biology
University of Virginia School of Medicine

Publications

Key Publications

Zegarra-Ruiz, DF., Kim, D., Norwood, K., Kim, M., Wu, W., Saldana-Morales, FB., Hill, AA., Majumdar, S., Orozco, S., Bell, R., Round, JL., Longman, RS., Egawa, T., Bettini, M., Diehl, GE. Thymic development of gut-microbiota-specific T cells. Nature (2021). doi.org/10.1038/s41586-021-03531-1.

Zegarra-Ruiz, DF., El Beidaq, A., Iñiguez, AJ., Lubrano Di Ricco, M., Manfredo Vieira, S., Ruff, WE., Mubiru, D., Fine, RL., Sterpka, J., Greiling, TM., Dehner, C., Kriegel, MA. A Diet-Sensitive Commensal Lactobacillus Strain Mediates TLR7-Dependent Systemic Autoimmunity. Cell Host Microbe (2019). doi: 10.1016/j.chom.2018.11.009.

Other Publications

Hill, AA., Kim, M., Zegarra-Ruiz, DF., Chang, LC., Norwood, KC., Assie, A., Wu, W., Renfroe, MC., Song, HW., Major, AM., Samuel BS., Hyser JM., Longman RS., Diehl, GE. Acute high fat diet impairs macrophage supported intestinal damage resolution. JCI Insight (2023). doi: 10.1172/jci.insight.164489.

Zegarra-Ruiz, DF., Kim, D., Norwood, K., Saldana-Morales, FB., Kim, M., Ng, C., Callaghan, R., Uddin, M., Chang, L., Longman, RS., Diehl, GE. Microbiota manipulation to increase macrophage IL-10 improves colitis and limits colitis-associated colorectal cancer. Gut Microbes (2022). doi: 10.1080/19490976.2022.2119054.

Wu, W., Zegarra-Ruiz, DF., Diehl, GE. Intestinal microbes in autoimmune and inflammatory disease. Front. Immunol (2020). doi: 10.3389/fimmu.2020.597966

Manfredo Vieira, S., Hiltensperger, M., Kumar, V., Zegarra-Ruiz, D., Dehner, C., Khan, N., Costa, FRC., Tiniakou, E., Greiling, T., Ruff, W., Barbieri, A., Kriegel, C., Mehta, SS., Knight, JR., Jain, D., Goodman, AL., Kriegel, MA. Translocation of a gut pathobiont drives autoimmunity in mice and humans. Science (2018). doi: 10.1126/science.aar7201.

Greiling, TM., Dehner, C., Chen, X., Hughes, K., Iñiguez, AJ., Boccitto, M., Ruiz, DZ., Renfroe, SC., Vieira, SM., Ruff, WE., Sim, S., Kriegel, C., Glanternik, J., Chen, X., Girardi, M., Degnan, P., Costenbader, KH., Goodman, AL., Wolin, SL., Kriegel, MA. Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus. Sci Transl Med (2018). doi: 10.1126/scitranslmed.aan2306.

A comprehensive list of Dr. Zegarra-Ruiz’s publications can be found on the NIH National Center for Biotechnology Information (NCBI) website:
https://www.ncbi.nlm.nih.gov/myncbi/daniel.zegarra%20ruiz.1/bibliography/public/