The Beirne B. Carter Center for Immunology Research (CIC) hosted its annual Carter Immunology Lecture on October 6, 2025. The lecture honors Beirne Carter, whose generosity provided the initial gift needed to establish our Research Center. This year, the CIC hosted Erika Pearce, PhD, Bloomberg Distinguished Professor at the Johns Hopkins University School of Medicine. She was hosted by the CIC’s Jie Sun, PhD, who had previously trained with Pearce.

In her lecture, “A Polyamine-mediated Posttranslational Modification That Governs Macrophage Tissue Residency,” Pearce demonstrated her expertise in immunometabolism. Her talk discussed how modifications to a protein, eukaryotic translation initiation factor 5A, regulates the future behavior of immune cells. Her work traced the downstream consequences of changes in this metabolic process into a host of organ systems. In appreciation for her excellent lecture and preeminence in immunometabolism, the CIC presented Pearce with a Jefferson Cup.
A reception followed the lecture in the Pinn Hall Conference Center atrium.
