Anne I. Sperling

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Primary Appointment

Professor, Medicine- Pulmonary and Critical Care Medicine

Education

  • AB, Biology, Smith College
  • PhD, Immunology, Tufts University, Boston, MA

Research Disciplines

Immunology, Translational Science

Research Interests

Immune Responses in asthma, pulmonary fibrosis, and lung injury.

Selected Publications

2022

Jia, G., Zhong, X., Im, H. K., Schoettler, N., Pividori, M., Hogarth, D. K., . . . Solway, J. (2022). Discerning asthma endotypes through comorbidity mapping.. Nature communications, 13(1), 6712. doi:10.1038/s41467-022-33628-8

Briquez, P. S., Rouhani, S. J., Yu, J., Pyzer, A. R., Trujillo, J., Dugan, H. L., . . . Swartz, M. A. (2022). Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity.. Science advances, 8(40), eabn3777. doi:10.1126/sciadv.abn3777

MacDonald, M. E., Weathered, R. K., Stewart, E. C., Magold, A. I., Mukherjee, A., Gurbuxani, S., . . . Swartz, M. A. (2022). Lymphatic coagulation and neutrophil extracellular traps in lung-draining lymph nodes of COVID-19 decedents.. Blood advances, bloodadvances.2022007798. doi:10.1182/bloodadvances.2022007798

Rahimi, R. A., Cho, J. L., Jakubzick, C. V., Khader, S. A., Lambrecht, B. N., Lloyd, C. M., . . . Singer, B. D. (2022). Advancing Lung Immunology Research An Official American Thoracic Society Workshop Report. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 67(1), E1-E18. doi:10.1165/rcmb.2022-0167ST

Barnes, H., Troy, L., Lee, C. T., Sperling, A., Strek, M., & Glaspole, I. (2022). Hypersensitivity pneumonitis: Current concepts in pathogenesis, diagnosis, and treatment. ALLERGY, 77(2), 442-453. doi:10.1111/all.15017

2021

Aneas, I., Decker, D. C., Howard, C. L., Sobreira, D. R., Sakabe, N. J., Blaine, K. M., . . . Nobrega, M. A. (2021). Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-26347-z

McMullen, P., Pytel, P., Snyder, A., Smith, H., Vickery, J., Brainer, J., . . . Mueller, J. (2021). A series of COVID-19 autopsies with clinical and pathologic comparisons to both seasonal and pandemic influenza. JOURNAL OF PATHOLOGY CLINICAL RESEARCH, 7(5), 459-470. doi:10.1002/cjp2.220

Kasal, D. N., Liang, Z., Hollinger, M. K., O'Leary, C. Y., Lisicka, W., Sperling, A. I., & Bendelac, A. (2021). A Gata3 enhancer necessary for ILC2 development and function. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(32). doi:10.1073/pnas.2106311118

Wu, D., Lee, T. -H., Huang, R. -T., Guzy, R. D., Schoettler, N., Adegunsoye, A., . . . Fang, Y. (2021). SARS-CoV-2 Infection Is Associated with Reduced Kr_uppel-like Factor 2 in Human Lung Autopsy. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 65(2), 222-226. doi:10.1165/rcmb.2020-0564LE

Krishack, P. A., Hollinger, M. K., Kuzel, T. G., Decker, T. S., Louviere, T. J., Hrusch, C. L., . . . Verhoef, P. A. (2021). IL-33-mediated Eosinophilia Protects against Acute Lung Injury. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 64(5), 569-578. doi:10.1165/rcmb.2020-0166OC

Maisel, K., Hrusch, C. L., Medellin, J. E. G., Potin, L., Chapel, D. B., Nurmi, H., . . . Swartz, M. A. (2021). Pro-lymphangiogenic VEGFR-3 signaling modulates memory T cell responses in allergic airway inflammation. MUCOSAL IMMUNOLOGY, 14(1), 144-151. doi:10.1038/s41385-020-0308-4

Wagar, L. E., Salahudeen, A., Constantz, C. M., Wendel, B. S., Lyons, M. M., Mallajosyula, V., . . . Davis, M. M. (2021). Modeling human adaptive immune responses with tonsil organoids. NATURE MEDICINE, 27(1), 125-+. doi:10.1038/s41591-020-01145-0

2020

Bhavani, S. V., Wolfe, K. S., Hrusch, C. L., Greenberg, J. A., Krishack, P. A., Lin, J., . . . Patel, B. K. (2020). Temperature Trajectory Subphenotypes Correlate With Immune Responses in Patients With Sepsis. CRITICAL CARE MEDICINE, 48(11), 1645-1653. doi:10.1097/CCM.0000000000004610

Adegunsoye, A., Alqalyoobi, S., Linderholm, A., Bowman, W. S., Lee, C. T., Pugashetti, J. V., . . . Oldham, J. M. (2020). Circulating Plasma Biomarkers of Survival in Antifibrotic-Treated Patients With Idiopathic Pulmonary Fibrosis. CHEST, 158(4), 1526-1534. doi:10.1016/j.chest.2020.04.066

Lee, T. -H., Yeh, C. -F., Lee, Y. -T., Shih, Y. -C., Chen, Y. -T., Hung, C. -T., . . . Yang, K. -C. (2020). Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGF beta signaling through TGFBR1 stabilization. NATURE COMMUNICATIONS, 11(1). doi:10.1038/s41467-020-18047-x

Si, Y., Tian, Q., Zhao, F., Kelly, S. H., Shores, L. S., Camacho, D. F., . . . Chong, A. S. (2020). Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and T(H)17 responses. SCIENCE ADVANCES, 6(32). doi:10.1126/sciadv.aba0995

Alqalyoobi, S., Adegunsoye, A., Linderholm, A., Hrusch, C., Cutting, C., Ma, S. -F., . . . Oldham, J. M. (2020). Circulating Plasma Biomarkers of Progressive Interstitial Lung Disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 201(2), 250-253. doi:10.1164/rccm.201907-1343LE

2019

Schoettler, N., Hrusch, C. L., Blaine, K. M., Sperling, A. I., & Ober, C. (2019). Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells. COMMUNICATIONS BIOLOGY, 2. doi:10.1038/s42003-019-0657-2

Sharma, A., Laxman, B., Naureckas, E. T., Hogarth, D. K., Sperling, A. I., Solway, J., . . . White, S. R. (2019). Associations between fungal and bacterial microbiota of airways and asthma endotypes. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 144(5), 1214-+. doi:10.1016/j.jaci.2019.06.025

Hrusch, C. L., Stein, M. M., Gozdz, J., Holbreich, M., von Mutius, E., Vercelli, D., . . . Sperling, A. I. (2019). T-cell phenotypes are associated with serum IgE levels in Amish and Hutterite children. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 144(5), 1391-+. doi:10.1016/j.jaci.2019.07.034

Tighe, R. M., Redente, E. F., Yu, Y. -R., Herold, S., Sperling, A. I., Curtis, J. L., . . . Allergy, A. T. S. A. (2019). Improving the Quality and Reproducibility of Flow Cytometry in the Lung An Official American Thoracic Society Workshop Report. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 61(2), 150-161. doi:10.1165/rcmb.2019-0191ST

Stein, M. M., Hrusch, C. L., Sperling, A. I., & Ober, C. (2019). Effects of an Fc gamma RIIA polymorphism on leukocyte gene expression and cytokine responses to anti-CD3 and anti-CD28 antibodies. GENES AND IMMUNITY, 20(6), 462-472. doi:10.1038/s41435-018-0038-8

White, S. R., Laxman, B., Naureckas, E. T., Hogarth, D. K., Solway, J., Sperling, A. I., & Ober, C. (2019). Evidence for an IL-6-high asthma phenotype in asthmatic patients of African ancestry. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 144(1), 304-+. doi:10.1016/j.jaci.2019.04.007

Reyfman, P. A., Walter, J. M., Joshi, N., Anekalla, K. R., McQuattie-Pimentel, A. C., Chiu, S., . . . Misharin, A. V. (2019). Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199(12), 1517-1536. doi:10.1164/rccm.201712-2410OC

Adegunsoye, A., Oldham, J. M., Sperling, A. I., Noth, I., Strek, M. E., & Chung, J. H. (2019). Prognostic Impact of Mediastinal Lymph Nodes in Interstitial Lung Diseases: Is Environmental Exposure the Offender? Reply. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199(8), 1041-1042. doi:10.1164/rccm.201811-2208LE

Krishack, P. A., Louviere, T. J., Decker, T. S., Kuzel, T. G., Greenberg, J. A., Camacho, D. F., . . . Verhoef, P. A. (2019). Protection against Staphylococcus aureus bacteremia-induced mortality depends on ILC2s and eosinophils. JCI INSIGHT, 4(6). doi:10.1172/jci.insight.124168

Adegunsoye, A., Oldham, J. M., Bonham, C., Hrusch, C., Nolan, P., Klejch, W., . . . Chung, J. H. (2019). Prognosticating Outcomes in Interstitial Lung Disease by Mediastinal Lymph Node Assessment An Observational Cohort Study with Independent Validation. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199(6), 747-759. doi:10.1164/rccm.201804-0761OC

2018

Williams, J. W., Ferreira, C. M., Blaine, K. M., Rayon, C., Velazquez, F., Tong, J., . . . Sperling, A. I. (2018). Non-apoptotic Fas (CD95) Signaling on T Cells Regulates the Resolution of Th2-Mediated Inflammation. FRONTIERS IN IMMUNOLOGY, 9. doi:10.3389/fimmu.2018.02521

Ferreira, C. M., Williams, J. W., Tong, J., Rayon, C., Blaine, K. M., & Sperling, A. I. (2018). Allergen Exposure in Lymphopenic Fas-Deficient Mice Results in Persistent Eosinophilia Due to Defects in Resolution of Inflammation. FRONTIERS IN IMMUNOLOGY, 9. doi:10.3389/fimmu.2018.02395

Hrusch, C. L., Manns, S. T., Bryazka, D., Casaos, J., Bonham, C. A., Jaffery, M. R., . . . Sperling, A. I. (2018). ICOS protects against mortality from acute lung injury through activation of IL-5(+) ILC2s. MUCOSAL IMMUNOLOGY, 11(1), 61-70. doi:10.1038/mi.2017.42

2017

Krishack, P. A., Wang, K., Rzhetsky, A., Solway, J., Sperling, A. I., & Verhoef, P. A. (2017). Preexisting Type 2 Immune Activation Protects against the Development of Sepsis. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 57(5), 628-630. doi:10.1165/rcmb.2017-0277LE

Ober, C., Sperling, A. I., von Mutius, E., & Vercelli, D. (2017). Immune development and environment: lessons from Amish and Hutterite children. CURRENT OPINION IN IMMUNOLOGY, 48, 51-60. doi:10.1016/j.coi.2017.08.003

White, S. R., Nicodemus-Johnson, J., Laxman, B., Denner, D. R., Naureckas, E. T., Hogarth, D. K., . . . Ober, C. (2017). Elevated levels of soluble human leukocyte antigen-G in the airways are a marker for a low-inflammatory endotype of asthma. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 140(3), 857-860. doi:10.1016/j.jaci.2017.02.031

2016

Nicodemus-Johnson, J., Myers, R. A., Sakabe, N. J., Sobreira, D. R., Hogarth, D. K., Naureckas, E. T., . . . Ober, C. (2016). DNA methylation in lung cells is associated with asthma endotypes and genetic risk. JCI INSIGHT, 1(20). doi:10.1172/jci.insight.90151

Adegunsoye, A., Hrusch, C. L., Bonham, C. A., Jaffrey, M. R., Blaine, K. M., Sullivan, M., . . . Sperling, A. I. (2016). Skewed Lung CCR4 to CCR6 CD4(+) T Cell Ratio in Idiopathic Pulmonary Fibrosis Is Associated with Pulmonary Function. FRONTIERS IN IMMUNOLOGY, 7. doi:10.3389/fimmu.2016.00516

Stein, M. M., Hrusch, C. L., Gozdz, J., Igartua, C., Pivniouk, V., Murray, S. E., . . . Sperling, A. I. (2016). Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children. NEW ENGLAND JOURNAL OF MEDICINE, 375(5), 411-421. doi:10.1056/NEJMoa1508749

Kariuki, S. N., Maranville, J. C., Baxter, S. S., Jeong, C., Nakagome, S., Hrusch, C. L., . . . Di Rienzo, A. (2016). Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells. PLOS ONE, 11(7). doi:10.1371/journal.pone.0159779

Denner, D. R., Sangwan, N., Becker, J. B., Hogarth, D. K., Oldham, J., Castillo, J., . . . White, S. R. (2016). Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 137(5), 1398-+. doi:10.1016/j.jaci.2015.10.017

Gozdz, J., Holbreich, M., Metwali, N., Thorne, P. S., Sperling, A. I., Martinez, F. D., . . . Vercelli, D. (2016). Amish and Hutterite Environmental Farm Products Have Opposite Effects on Experimental Models of Asthma. ANNALS OF THE AMERICAN THORACIC SOCIETY, 13, S99. Retrieved from https://www.webofscience.com/

Nicodemus-Johnson, J., Naughton, K. A., Sudi, J., Hogarth, K., Naurekas, E. T., Nicolae, D. L., . . . Ober, C. (2016). Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193(4), 376-385. doi:10.1164/rccm.201506-1243OC

Verhoef, P. A., Constantinides, M. G., McDonald, B. D., Jr, U. J. F., Sperling, A. I., & Bendelac, A. (2016). Intrinsic functional defects of type 2 innate lymphoid cells impair innate allergic inflammation in promyelocytic leukemia zinc finger (PLZF)-deficient mice. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 137(2), 591-+. doi:10.1016/j.jaci.2015.07.050

2015

Edelblum, K. L., Singh, G., Odenwald, M. A., Lingaraju, A., El Bissati, K., McLeod, R., . . . Turner, J. R. (2015). gamma delta Intraepithelial Lymphocyte Migration Limits Transepithelial Pathogen Invasion and Systemic Disease in Mice. GASTROENTEROLOGY, 148(7), 1417-1426. doi:10.1053/j.gastro.2015.02.053

Hrusch, C. L., Tjota, M. Y., & Sperling, A. I. (2015). The Role of Dendritic Cells and Monocytes in the Maintenance and Loss of Respiratory Tolerance. CURRENT ALLERGY AND ASTHMA REPORTS, 15(1). doi:10.1007/s11882-014-0494-9

2014

Broz, M. L., Binnewies, M., Boldajipour, B., Nelson, A. E., Pollack, J. L., Erle, D. J., . . . Krummel, M. F. (2014). Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity (vol 26, pg 638, 2014). CANCER CELL, 26(6), 938. doi:10.1016/j.ccell.2014.11.010

Tjota, M. Y., & Sperling, A. I. (2014). Distinct dendritic cell subsets actively induce Th2 polarization. CURRENT OPINION IN IMMUNOLOGY, 31, 44-50. doi:10.1016/j.coi.2014.09.006

Sperling, A. I., & Ansel, K. M. (2014). Editorial overview: Allergy and hypersensitivity. CURRENT OPINION IN IMMUNOLOGY, 31, IX-XI. doi:10.1016/j.coi.2014.10.011

Broz, M. L., Binnewies, M., Boldajipour, B., Nelson, A. E., Pollack, J. L., Erle, D. J., . . . Krummel, M. F. (2014). Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity. CANCER CELL, 26(5), 638-652. doi:10.1016/j.ccell.2014.09.007

Tjota, M. Y., Hrusch, C. L., Blaine, K. M., Williams, J. W., Barrett, N. A., & Sperling, A. I. (2014). Signaling through FcR gamma-associated receptors on dendritic cells drives IL-33-dependent T(H)2-type responses. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 134(3), 706-+. doi:10.1016/j.jaci.2014.06.013

Chen, B., Moore, T. V., Li, Z., Sperling, A. I., Zhang, C., Andrade, J., . . . Solway, J. (2014). Gata5 Deficiency Causes Airway Constrictor Hyperresponsiveness in Mice. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 50(4), 787-795. doi:10.1165/rcmb.2013-0294OC

Flor, A. C., Williams, J. H., Blaine, K. M., Duggan, R. C., Sperling, A. I., Schwartz, D. A., & Kron, S. J. (2014). DNA-Directed Assembly of Antibody-Fluorophore Conjugates for Quantitative Multiparametric Flow Cytometry. CHEMBIOCHEM, 15(2), 267-275. doi:10.1002/cbic.201300464

2013

Williams, J. W., Tjota, M. Y., Clay, B. S., Lugt, B. V., Bandukwala, H. S., Hrusch, C. L., . . . Sperling, A. I. (2013). Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation. NATURE COMMUNICATIONS, 4. doi:10.1038/ncomms3990

Cannon, J. L., Asperti-Boursin, F., Letendre, K. A., Brown, I. K., Korzekwa, K. E., Blaine, K. M., . . . Moses, M. E. (2013). PKC theta Regulates T Cell Motility via Ezrin-Radixin-Moesin Localization to the Uropod. PLOS ONE, 8(11). doi:10.1371/journal.pone.0078940

Williams, J. W., Yau, D., Sethakorn, N., Kach, J., Reed, E. B., Moore, T. V., . . . Dulin, N. O. (2013). RGS3 controls T lymphocyte migration in a model of Th2-mediated airway inflammation. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 305(10), L693-L701. doi:10.1152/ajplung.00214.2013

Wu, Q., Gardiner, G. J., Berry, E., Wagner, S. R., Lu, T., Clay, B. S., . . . Shilling, R. A. (2013). ICOS-Expressing Lymphocytes Promote Resolution of CD8-Mediated Lung Injury in a Mouse Model of Lung Rejection. PLOS ONE, 8(8). doi:10.1371/journal.pone.0072955

Nicodemus-Johnson, J., Laxman, B., Stern, R. K., Sudi, J., Tierney, C. N., Norwick, L., . . . Ober, C. (2013). Maternal asthma and microRNA regulation of soluble HLA-G in the airway. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 131(6), 1496-+. doi:10.1016/j.jaci.2013.01.037

Kach, J., Sandbo, N., Sethakorn, N., Williams, J., Reed, E. B., La, J., . . . Dulin, N. O. (2013). Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 304(11), L757-L764. doi:10.1152/ajplung.00262.2012

Tjota, M. Y., Williams, J. W., Lu, T., Clay, B. S., Byrd, T., Hrusch, C. L., . . . Sperling, A. I. (2013). IL-33-dependent induction of allergic lung inflammation by Fc gamma RIII signaling. JOURNAL OF CLINICAL INVESTIGATION, 123(5), 2287-2297. doi:10.1172/JCI63802

Shilling, R. A., Williams, J. W., Perera, J., Berry, E., Wu, Q., Cummings, O. W., . . . Huang, H. (2013). Autoreactive T and B Cells Induce the Development of Bronchus-Associated Lymphoid Tissue in the Lung. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 48(4), 406-414. doi:10.1165/rcmb.2012-0065OC

Patterson, K. C., Franek, B. S., Mueller-Quernheim, J., Sperling, A. I., Sweiss, N. J., & Niewold, T. B. (2013). Circulating cytokines in sarcoidosis: Phenotype-specific alterations for fibrotic and non-fibrotic pulmonary disease. CYTOKINE, 61(3), 906-911. doi:10.1016/j.cyto.2012.12.016

2012

Patterson, K. C., Hogarth, K., Husain, A. N., Sperling, A. I., & Niewold, T. B. (2012). The clinical and immunologic features of pulmonary fibrosis in sarcoidosis. TRANSLATIONAL RESEARCH, 160(5), 321-331. doi:10.1016/j.trsl.2012.03.005

Edelblum, K. L., Shen, L., Weber, C. R., Marchiando, A. M., Clay, B. S., Wang, Y., . . . Turner, J. R. (2012). Dynamic migration of gamma delta intraepithelial lymphocytes requires occludin. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(18), 7097-7102. doi:10.1073/pnas.1112519109

Zloza, A., Kohlhapp, F. J., Lyons, G. E., Schenkel, J. M., Moore, T. V., Lacek, A. T., . . . Guevara-Patino, J. A. (2012). NKG2D signaling on CD8(+) T cells represses T-bet and rescues CD4-unhelped CD8(+) T cell memory recall but not effector responses. NATURE MEDICINE, 18(3), 422-U184. doi:10.1038/nm.2683

Williams, J. W., Tjota, M. Y., & Sperling, A. I. (2012). The contribution of allergen-specific IgG to the development of th2-mediated airway inflammation.. Journal of allergy, 2012, 236075. doi:10.1155/2012/236075

2011

Moore, T. V., Clay, B. S., Cannon, J. L., Histed, A., Shilling, R. A., & Sperling, A. I. (2011). Inducible Costimulator Controls Migration of T Cells to the Lungs via Down-Regulation of CCR7 and CD62L. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 45(4), 843-850. doi:10.1165/rcmb.2010-0466OC

Cannon, J. L., Mody, P. D., Blaine, K. M., Chen, E. J., Nelson, A. D., Sayles, L. J., . . . Sperling, A. I. (2011). CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation. MOLECULAR BIOLOGY OF THE CELL, 22(7), 954-963. doi:10.1091/mbc.E10-07-0586

Moore, T. V., Clay, B. S., Ferreira, C. M., Williams, J. W., Rogozinska, M., Cannon, J. L., . . . Sperling, A. I. (2011). Protective Effector Memory CD4 T Cells Depend on ICOS for Survival. PLOS ONE, 6(2). doi:10.1371/journal.pone.0016529

2010

Bhorade, S. M., Chen, H., Molinero, L., Liao, C., Garrity, E. R., Vigneswaran, W. T., . . . Alegre, M. -L. (2010). Decreased Percentage of CD4(+) FoxP3(+) Cells in Bronchoalveolar Lavage From Lung Transplant Recipients Correlates With Development of Bronchiolitis Obliterans Syndrome. TRANSPLANTATION, 90(5), 540-546. doi:10.1097/TP.0b013e3181e8dabe

Tong, J., Clay, B. S., Ferreira, C. M., Bandukwala, H. S., Moore, T. V., Blaine, K. M., . . . Sperling, A. I. (2010). Fas Ligand Expression on T Cells Is Sufficient to Prevent Prolonged Airway Inflammation in a Murine Model of Asthma. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 43(3), 342-348. doi:10.1165/rcmb.2008-0454OC

Shaffer, M. H., Huang, Y., Corbo, E., Wu, G. F., Velez, M., Choi, J. K., . . . Burkhardt, J. K. (2010). Ezrin Is Highly Expressed in Early Thymocytes, but Dispensable for T Cell Development in Mice. PLOS ONE, 5(8). doi:10.1371/journal.pone.0012404

Lacey, E. H., Lott, S. N., Snider, S. F., Sperling, A., & Friedman, R. B. (2010). Multiple Oral Re-reading treatment for alexia: The parts may be greater than the whole. NEUROPSYCHOLOGICAL REHABILITATION, 20(4), 601-623. doi:10.1080/09602011003710993

Lacey, E. H., Lott, S. N., Snider, S. F., Sperling, A., & Friedman, R. B. (2010). Multiple Oral Re-reading treatment for alexia: The parts may be greater than the whole (vol 20, pg 601, 2010). NEUROPSYCHOLOGICAL REHABILITATION, 20(6), 940. doi:10.1080/09602011.2010.530784