Angela M. Taylor

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Primary Appointment

Professor, Medicine- Cardiovascular Medicine

Education

  • Fellowship, Cardiovascular Medicine & Interventional Cardiology, University of Virginia
  • Residency, Internal Medicine, Medical University of South Carolina
  • MD, Medical College of South Carolina

Research Interests

Diabetic cardiovascular disease - early diagnosis and prevention; Women's heart disease.

Research Description

Project 1: Early Noninvasive Detection of Myocardial Microvascular Dysfunction in Diabetes
Brief Description:
Type 2 diabetes has become an epidemic in the United States. Cardiovascular disease is the most common cause of death in this population and is two- to four-fold higher than in the general population. This increased risk is at least partially attributable to the high prevalence of the metabolic syndrome with its multiple coronary heart disease risk factors including central obesity, hypertension, glucose intolerance, chronic inflammation, and dyslipidemia.
However, recent trials have demonstrated that traditional risk factors alone are not completely predictive of disease burden particularly early in the disease process prior to the development of flow-limiting coronary stenoses.
Thus, diagnosis and prevention of cardiovascular disease development has been elusive in this high-risk population. It is not entirely clear which factors, known or novel, contribute the most in very early disease and which therapies may be most beneficial.
It has been suggested that microvascular dysfunction, a composite of endothelial dysfunction, abnormal blood cell rheology, and abnormal blood viscosity, precedes the development of overt coronary stenoses and contributes to increased cardiovascular risk very early in disease development. Microvascular reactivity is affected by many aspects of the metabolic syndrome. Microvascular reactivity can be measured invasively at the time of cardiac catheterization by measuring myocardial blood flow and calculating the coronary flow reserve (CFR). Commonly used noninvasive tools may not be adequate to evaluate microvascular function in the heart at baseline or in response to therapy. The American Diabetes Association has recently released a consensus statement stating that better approaches are needed to screen for and identify coronary artery disease in patients with diabetes.
Myocardial contrast echocardiography (MCE) and cardiac magnetic resonance imaging (CMR) provide noninvasive technology capable of directly measuring microvascular function within the heart. Our preliminary data with these modalities shows significantly reduced microvascular function in diabetes in the absence of significant coronary stenoses.
Prior to development of stenoses in the coronary arteries, plaque accumulates via positive remodeling preserving the lumen. This can be detected invasively through the use of intravascular ultrasound (IVUS). Coronary CT is a potential noninvasive modality able to assess this early remodeling process, but it requires a substantial radiation dose and iodinated contrast dye. In addition, CT requires calcification to have occurred within the plaque, a finding believed to occur well into the life of the plaque. It is unclear how early plaque development is related to microvascular function and if stabilization or regression of plaque with available therapies improves microvascular function.
The overall hypothesis is that CMR will predict invasive findings on CFR and IVUS providing a noninvasive mechanism to diagnose microvascular dysfunciton and thus early coronary disease.
Secondary objectives will include demonstrating that CMR can be used to follow microvascular function noninvasively over time and that risk factors for the metabolic syndrome will predict disease burden using invasive and noninvasive meaasurements contrary to recent literature using standard noninvasive diagnostic methods. Such techniques may allow earlier noninvasive detection of disease as well as tailor treatment early in the disease process making prevention more cost effective.
The specific aims of this proposal are as follows:
1.To assess whether CMR will predict invasive findings with CFR and IVUS. The hypothesis is that MRI will predict findings on IVUS and CFR, providing a novel noninvasive mechanism for direct detection of early coronary artery disease.
2. To assess whether changes in microvascular flow over time, and thus early coronary disease, can be followed noninvasively by CMR. The hypothesis is that changes in microvascular function measured noninvasively with CMR will predict invasive measurements using CFR and that improvements in microvascular function will predict plaque stabilization and/or regression as measured by IVUS.
3.To assess whether risk factors for coronary artery disease, both known and novel, predict quantitative and qualitative plaque characteristics on IVUS and alterations in myocardial blood flow on CMR and CFR. As CMR has the ability to detect global dysfunction, as opposed to current commonly used noninvasive techniques, the hypothesis is that risk factors for cardiovascular disease will predict disease burden on IVUS as well as CMR and CFR and that improvements in risk factors will predict improvements on invasive and noninvasive measurements.
Project 2: Mechanism of Acute Coronary Syndromes in Premenopausal Women
Brief description: The prevalence of cardiovascular disease and myocardial infarction is higher in men compared to women for every age group. Despite this, women have a 2-fold increase in cardiovascular mortality compared to men. This increase in mortality cannot be explained by age, comorbidities, therapy, or revascularization. Further, women are more likely to have a larger symptom burden for a given amount of angiographically detectable disease. Many women without angiographically detectable disease have demonstrable ischemia and an increase in adverse cardiovascular events. It has been suggested that this may be due to microvascular dysfunction, a composite of endothelial dysfunction, abnormal blood cell rheology, and abnormal blood cell viscosity. It has been demonstrated in women by intravascular ultrasound (IVUS) that large amounts of plaque can be stored in the artery wall prior to overt stenosis formation and that this plaque may contribute to dysfunction in the microvasculature measured invasively during cardiac catheterization. It has been suggested that this process may be more active in cardiovascular disease in women, particularly in the presence of the metabolic syndrome. It has further been suggested that women often develop acute coronary syndromes in mostly fibrous areas via plaque erosion as opposed to plaque rupture in lipid rich areas. This appears to be particularly true in premenopausal women. It is not completely understand what differences exist between men and women in terms of plaque composition and intimal changes during acute coronary syndromes that drive the increased morbidity and mortality in women. In order to initiate proper therapy in women, a better understanding is needed of the pathophysiology of coronary artery disease in the female gender. Technology now exists that will allow both visualization of the artery composition and the luminal surface. Intravascular ultrasound (IVUS-VH) with virtual histology capabilities allows in vivo characterization of plaque type. Optical coherence tomography (OCT) further allows a more detailed view of the luminal surface of the artery and can identify areas of plaque erosion and white thrombus. Together, these tools represent a powerful method whereby to fully examine differences in plaque characteristics between men and women, potentially redirecting therapy.
Further, populations in studies of drug therapy and risk factor modification in the arena of cardiovascular disease have been predominantly male. Further study is needed to determine if current therapy for cardiovascular risk factor reduction is as affective in women as compared to men at the level of the plaque.
The overall hypothesis of this study is that plaque morphology in acute coronary syndromes will differ significantly between premenopausal women and age-matched men and that measurement of traditional cardiovascular risk factors will be less predictive of findings on IVUS and OCT in premenopausal women compared to men.
Specific aims:
1. To demonstrate that IVUS and OCT, used together, can successfully differentiate plaque characteristics in men and premenopausal women with acute coronary syndromes.
2. To assess whether traditional risk factors predict quantitative and qualitative findings on IVUS and OCT in men and women.
3. To investigate if novel risk factors may be linked to acute coronary syndromes in women.

Selected Publications

2024

Crawford, A. N., Taylor, A., Patterson, J., Okpeku, A., & Donohoe, K. L. (2024). An active-learning laboratory focused on critical care topics.. Currents in pharmacy teaching & learning, 16(6), 469-475. doi:10.1016/j.cptl.2024.03.009

Chatterjee, N., Komaravolu, R. K., Durant, C. P., Wu, R., Mcskimming, C., Drago, F., . . . Hedrick, C. C. (2024). Single Cell High Dimensional Analysis of Human Peripheral Blood Mononuclear Cells Reveals Unique Intermediate Monocyte Subsets Associated with Sex Differences in Coronary Artery Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25(5). doi:10.3390/ijms25052894

2023

Pattarabanjird, T., Srikakulapu, P., Ransegnola, B., Marshall, M. A., Ghosheh, Y., Gulati, R., . . . Mcnamara, C. A. (2024). Single-cell profiling of CD11c+B cells in atherosclerosis. FRONTIERS IN IMMUNOLOGY, 14. doi:10.3389/fimmu.2023.1296668

Pattarabanjird, T., Nguyen, A. T., Mcskimming, C., Dinh, H. Q., Marshall, M. A., Ghosheh, Y., . . . Mcnamara, C. A. (2023). Human circulating CD24hi marginal zone B cells produce IgM targeting atherogenic antigens and confer protection from vascular disease (vol 2, pg 1003, 2023). NATURE CARDIOVASCULAR RESEARCH, 2(12), 1328. doi:10.1038/s44161-023-00390-z

Pattarabanjird, T., Nguyen, A. T., McSkimming, C., Dinh, H. Q., Marshall, M. A., Ghosheh, Y., . . . Mcnamara, C. A. (2023). Human circulating CD24hi marginal zone B cells produce IgM targeting atherogenic antigens and confer protection from vascular disease. NATURE CARDIOVASCULAR RESEARCH, 2(11), 1003-+. doi:10.1038/s44161-023-00356-1

2022

Saigusa, R., Vallejo, J., Gulati, R., Suthahar, S. S. A., Suryawanshi, V., Alimadadi, A., . . . Ley, K. (2022). Sex Differences in Coronary Artery Disease and Diabetes Revealed by scRNA-Seq and CITE-Seq of Human CD4+T Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(17). doi:10.3390/ijms23179875

Sharma, P., Shah, K., Loomba, J., Patel, A., Mallawaarachchi, I., Blazek, O., . . . Mazimba, S. (2022). The impact of COVID-19 on clinical outcomes among acute myocardial infarction patients undergoing early invasive treatment strategy. CLINICAL CARDIOLOGY, 45(10), 1070-1078. doi:10.1002/clc.23908

Li, J., Taylor, A. M., Manichaikul, A., Angle, J. F., & Shi, W. (2022). Reticulocalbin 2 as a Potential Biomarker and Therapeutic Target for Atherosclerosis. CELLS, 11(7). doi:10.3390/cells11071107

Lozano, P. F. R., Kaso, E. R., Bourque, J. M., Morsy, M., Taylor, A. M., Villines, T. C., . . . Salerno, M. (2022). Cardiovascular Imaging for Ischemic Heart Disease in Women Time for a Paradigm Shift. JACC-CARDIOVASCULAR IMAGING, 15(8), 1488-1501. doi:10.1016/j.jcmg.2022.01.006

Ghumman, S. S., Ibrahim, S., Taylor, A. M., Fauber, N., & Ragosta, M. (2022). The "July Effect" in the Cardiac Catheterization Laboratory. AMERICAN JOURNAL OF CARDIOLOGY, 170, 160-165. doi:10.1016/j.amjcard.2022.01.032

Pattarabanjird, T., Marshall, M., Upadhye, A., Srikakulapu, P., Garmey, J. C., Haider, A., . . . McNamara, C. A. (2022). B-1b Cells Possess Unique bHLH-Driven P62-Dependent Self-Renewal and Atheroprotection. CIRCULATION RESEARCH, 130(7), 981-993. doi:10.1161/CIRCRESAHA.121.320436

2021

Basir, M. B., Lemor, A., Gorgis, S., Taylor, A. M., Tehrani, B., Truesdell, A. G., . . . O'Neill, W. W. (2022). Vasopressors independently associated with mortality in acute myocardial infarction and cardiogenic shock. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 99(3), 650-657. doi:10.1002/ccd.29895

Gaddis, D. E., Padgett, L. E., Wu, R., Nguyen, A., McSkimming, C., Dinh, H. Q., . . . Hedrick, C. C. (2021). Atherosclerosis Impairs Naive CD4 T-Cell Responses via Disruption of Glycolysis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 41(9), 2387-2398. doi:10.1161/ATVBAHA.120.314189

Kassiteridi, C., Cole, J. E., Griseri, T., Falck-Hansen, M., Goddard, M. E., Seneviratne, A. N., . . . Monaco, C. (2021). CD200 Limits Monopoiesis and Monocyte Recruitment in Atherosclerosis. CIRCULATION RESEARCH, 129(2), 280-295. doi:10.1161/CIRCRESAHA.119.316062

Pan, J. A., Robinson, A. A., Yang, Y., Lozano, P. R., McHugh, S., Holland, E. M., . . . Salerno, M. (2021). Diagnostic Accuracy of Spiral Whole-Heart Quantitative Adenosine Stress Cardiovascular Magnetic Resonance With Motion Compensated L1-SPIRIT. JOURNAL OF MAGNETIC RESONANCE IMAGING, 54(4), 1268-1279. doi:10.1002/jmri.27620

Upadhya, B., Pajewski, N. M., Rocco, M. V., Hundley, W. G., Aurigemma, G., Hamilton, C. A., . . . Kitzman, D. W. (2021). Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART. HYPERTENSION, 77(5), 1571-1580. doi:10.1161/HYPERTENSIONAHA.120.16676

Shah, K. P., Peruri, A., Kanneganti, M., Gorsch, L., Ramcharitar, R., Williams, C., . . . Sharma, A. M. (2021). Fibromuscular dysplasia: A comprehensive review on evaluation and management and role for multidisciplinary comprehensive care and patient input model. SEMINARS IN VASCULAR SURGERY, 34(1), 89-96. doi:10.1053/j.semvascsurg.2021.02.009

Shields, M. C., Ouellette, M., Kiefer, N., Kohan, L., Taylor, A. M., Ailawadi, G., & Ragosta, M. (2021). Characteristics and outcomes of surgically ineligible patients with multivessel disease treated with percutaneous coronary intervention. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 98(7), 1223-1229. doi:10.1002/ccd.29508

Pattarabanjird, T., Wilson, J. M., Erickson, L. D., Workman, L. J., Qiao, H., Ghosheh, Y., . . . McNamara, C. A. (2022). Chemokine Receptor Activation Enhances Memory B Cell Class Switching Linked to IgE Sensitization to Alpha Gal and Cardiovascular Disease. FRONTIERS IN CARDIOVASCULAR MEDICINE, 8. doi:10.3389/fcvm.2021.791028

Srikakulapu, P., Upadhye, A., Drago, F., Perry, H. M., Bontha, S. V., McSkimming, C., . . . McNamara, C. A. (2021). Chemokine Receptor-6 Promotes B-1 Cell Trafficking to Perivascular Adipose Tissue, Local IgM Production and Atheroprotection. FRONTIERS IN IMMUNOLOGY, 12. doi:10.3389/fimmu.2021.636013

2020

Pattarabanjird, T., Cress, C., Nguyen, A., Taylor, A., Bekiranov, S., & McNamara, C. (2020). A Machine Learning Model Utilizing a Novel SNP Shows Enhanced Prediction of Coronary Artery Disease Severity. GENES, 11(12). doi:10.3390/genes11121446

Padgett, L. E., Dinh, H. Q., Wu, R., Gaddis, D. E., Araujo, D. J., Winkels, H., . . . Hedrick, C. C. (2020). Naive CD8+ T Cells Expressing CD95 Increase Human Cardiovascular Disease Severity. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 40(12), 2845-2859. doi:10.1161/ATVBAHA.120.315106

Ragosta, M., Boehm, R., Shields, M., & Taylor, A. M. (2021). Intentional removal of erroneously deployed coronary stents: A case series and review of the literature. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 97(4), 670-674. doi:10.1002/ccd.29256

2019

McNair, P. W., Parker, A., Taylor, A., Battle, R., Norton, P., & Sharma, A. M. (2020). Spontaneous Coronary Artery Dissection and Its Association With Fibromuscular Dysplasia and Other Vascular Abnormalities. AMERICAN JOURNAL OF CARDIOLOGY, 125(1), 34-39. doi:10.1016/j.amjcard.2019.09.043

Upadhye, A., Srikakulapu, P., Gonen, A., Hendrikx, S., Perry, H. M., Anh, N., . . . McNamara, C. A. (2019). Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis. CIRCULATION RESEARCH, 125(10), E55-E70. doi:10.1161/CIRCRESAHA.119.315786

Hamers, A. A. J., Dinh, H. Q., Thomas, G. D., Marcovecchio, P., Blatchley, A., Nakao, C. S., . . . Hedrick, C. C. (2019). Human Monocyte Heterogeneity as Revealed by High-Dimensional Mass Cytometry. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 39(1), 25-36. doi:10.1161/ATVBAHA.118.311022

2018

Gonen, A., Choi, S. -H., Phuong, M., Agatisa-Boyle, C., Acks, D., Taylor, A. M., . . . Miller, Y. I. (2019). A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma1[S]. JOURNAL OF LIPID RESEARCH, 60(2), 436-445. doi:10.1194/jlr.D090852

Wilson, J. M., Nguyen, A. T., Schuyler, A. J., Commins, S. P., Taylor, A. M., Platts-Mills, T. A. E., & McNamara, C. A. (2018). IgE to the Mammalian Oligosaccharide Galactose--1,3-Galactose Is Associated With Increased Atheroma Volume and Plaques With Unstable CharacteristicsBrief Report. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 38(7), 1665-1669. doi:10.1161/ATVBAHA.118.311222

Smith, L., Peters, A., Mazimba, S., Ragosta, M., & Taylor, A. M. (2018). Outcomes of patients with cardiogenic shock treated with TandemHeart® percutaneous ventricular assist device: Importance of support indication and definitive therapies as determinants of prognosis. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 92(6), 1173-1181. doi:10.1002/ccd.27650

Gaddis, D. E., Padgett, L. E., Wu, R., McSkimming, C., Romines, V., Taylor, A. M., . . . Hedrick, C. C. (2018). Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis. NATURE COMMUNICATIONS, 9. doi:10.1038/s41467-018-03493-5

Zorach, B., Shaw, P. W., Bourque, J., Kuruvilla, S., Balfour, P. C., Yang, Y., . . . Salerno, M. (2018). Quantitative cardiovascular magnetic resonance perfusion imaging identifies reduced flow reserve in microvascular coronary artery disease. JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, 20. doi:10.1186/s12968-018-0435-1

Kothari, H., Nguyen, A. T., Yang, X., Hisada, Y., Tsimikas, S., Mackman, N., . . . McNamara, C. A. (2018). Association of D-dimer with Plaque Characteristics and Plasma Biomarkers of Oxidation-Specific Epitopes in Stable Subjects with Coronary Artery Disease. JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 11(3), 221-229. doi:10.1007/s12265-018-9790-4

2017

Marcovecchio, P. M., Thomas, G. D., Mikulski, Z., Ehinger, E., Mueller, K. A. L., Blatchley, A., . . . Hedrick, C. C. (2017). Scavenger Receptor CD36 Directs Nonclassical Monocyte Patrolling Along the Endothelium During Early Atherogenesis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 37(11), 2043-+. doi:10.1161/ATVBAHA.117.309123

Thomas, G. D., Hamers, A. A. J., Nakao, C., Marcovecchio, P., Taylor, A. M., McSkimming, C., . . . Hedrick, C. C. (2017). Human Blood Monocyte Subsets A New Gating Strategy Defined Using Cell Surface Markers Identified by Mass Cytometry. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 37(8), 1548-+. doi:10.1161/ATVBAHA.117.309145

Malin, S. K., Kaplan, J. L., Meng, L., Garmey, J. C., Kirby, J. L., Taylor, A. M., . . . McNamara, C. A. (2017). Age increases MCP-1 level in association with bariatric surgery operating time and metabolic risk severity. OBESITY SCIENCE & PRACTICE, 3(2), 193-200. doi:10.1002/osp4.105

Srikakulapu, P., Upadhye, A., Rosenfeld, S. M., Marshall, M. A., McSkimming, C., Hickman, A. W., . . . McNamara, C. A. (2017). Perivascular Adipose Tissue Harbors Atheroprotective IgM-Producing B Cells. FRONTIERS IN PHYSIOLOGY, 8. doi:10.3389/fphys.2017.00719

2016

Taylor, A. M. (2016). The Resurrection of Myeloperoxidase as a Therapeutic Target: Is it Lazarus or Just an Apparition?. JACC. Basic to translational science, 1(7), 644-646. doi:10.1016/j.jacbts.2016.10.003

Hisada, Y., Alexander, W., Kasthuri, R., Voorhees, P., Mobarrez, F., Taylor, A., . . . Mackman, N. (2016). Measurement of microparticle tissue factor activity in clinical samples: A summary of two tissue factor-dependent FXa generation assays (vol 139, pg 90, 2016). THROMBOSIS RESEARCH, 147, 63. doi:10.1016/j.thromres.2016.09.009

Cheng, H. -Y., Gaddis, D. E., Wu, R., McSkimming, C., Haynes, L. D., Taylor, A. M., . . . Hedrick, C. C. (2016). Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. JOURNAL OF CLINICAL INVESTIGATION, 126(9), 3236-3246. doi:10.1172/JCI83136

Harmon, D. B., Srikakulapu, P., Kaplan, J. L., Oldham, S. N., McSkimming, C., Garmey, J. C., . . . McNamara, C. A. (2016). Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 36(4), 682-691. doi:10.1161/ATVBAHA.116.307166

Hisada, Y., Alexander, W., Kasthuri, R., Voorhees, P., Mobarrez, F., Taylor, A., . . . Mackman, N. (2016). Measurement of microparticle tissue factor activity in clinical samples: A summary of two tissue factor-dependent FXa generation assays. THROMBOSIS RESEARCH, 139, 90-97. doi:10.1016/j.thromres.2016.01.011

2015

Barbato, E., Barton, P. J., Bartunek, J., Huber, S., Ibanez, B., Judge, D. P., . . . Hall, J. L. (2015). Review and Updates in Regenerative and Personalized Medicine, Preclinical Animal Models, and Clinical Care in Cardiovascular Medicine. JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 8(8), 466-474. doi:10.1007/s12265-015-9657-x

Rosenfeld, S. M., Perry, H. M., Gonen, A., Prohaska, T. A., Srikakulapu, P., Grewal, S., . . . McNamara, C. A. (2015). B-1b Cells Secrete Atheroprotective IgM and Attenuate Atherosclerosis. CIRCULATION RESEARCH, 117(3), E28-E39. doi:10.1161/CIRCRESAHA.117.306044

Taylor, A. M., & Ragosta, M. (2015). Understanding Left Main Disease: Will the Right SYNTAX Help Us EXCEL in (PRE)COMBAT?. JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 8(4), 209-210. doi:10.1007/s12265-015-9635-3

2014

Salerno, M., Taylor, A., Yang, Y., Kuruvilla, S., Ragosta, M., Meyer, C. H., & Kramer, C. M. (2014). Adenosine Stress Cardiovascular Magnetic Resonance With Variable-Density Spiral Pulse Sequences Accurately Detects Coronary Artery Disease Initial Clinical Evaluation. CIRCULATION-CARDIOVASCULAR IMAGING, 7(4), 639-U109. doi:10.1161/CIRCIMAGING.113.001584

Barbato, E., Lara-Pezzi, E., Stolen, C., Taylor, A., Barton, P. J., Bartunek, J., . . . Hall, J. L. (2014). Advances in Induced Pluripotent Stem Cells, Genomics, Biomarkers, and Antiplatelet Therapy Highlights of the Year in JCTR 2013. JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 7(5), 518-525. doi:10.1007/s12265-014-9555-7

West-Pollak, A., Then, E. P., Podesta, C., Hedelt, A., Perry, M. L., Izarnotegui, W. V., . . . Taylor, A. M. (2014). Impact of a novel community-based lifestyle intervention program on type 2 diabetes and cardiovascular risk in a resource-poor setting in the Dominican Republic. INTERNATIONAL HEALTH, 6(2), 118-124. doi:10.1093/inthealth/iht039

Manichaikul, A., Rich, S. S., Perry, H., Yeboah, J., Law, M., Davis, M., . . . Taylor, A. M. (2014). A Functionally Significant Polymorphism in ID3 Is Associated with Human Coronary Pathology. PLOS ONE, 9(3). doi:10.1371/journal.pone.0090222

2013

Choi, S. -H., Yin, H., Ravandi, A., Armando, A., Dumlao, D., Kim, J., . . . Miller, Y. I. (2013). Polyoxygenated Cholesterol Ester Hydroperoxide Activates TLR4 and SYK Dependent Signaling in Macrophages. PLOS ONE, 8(12). doi:10.1371/journal.pone.0083145

2012

Bourque, J. M., Schietinger, B. J., Kennedy, J. L., Pearce, E. A., Christopher, J. M., Taylor, A. M., . . . Kramer, C. M. (2012). Usefulness of Cardiovascular Magnetic Resonance Imaging of the Superficial Femoral Artery for Screening Patients With Diabetes Mellitus for Atherosclerosis. AMERICAN JOURNAL OF CARDIOLOGY, 110(1), 50-56. doi:10.1016/j.amjcard.2012.02.048

2011

Bunch, T. J., Darby, A., May, H. T., Ragosta, M., Lim, D. S., Taylor, A. M., . . . Mahapatra, S. (2012). Efficacy and safety of ventricular tachycardia ablation with mechanical circulatory support compared with substrate-based ablation techniques. EUROPACE, 14(5), 709-714. doi:10.1093/europace/eur347

Keeley, E. C., Moorman, J. R., Liu, L., Gimple, L. W., Lipson, L. C., Ragosta, M., . . . Strieter, R. M. (2011). Plasma Chemokine Levels Are Associated with the Presence and Extent of Angiographic Coronary Collaterals in Chronic Ischemic Heart Disease. PLOS ONE, 6(6). doi:10.1371/journal.pone.0021174

2010

Enkiri, S. A., Taylor, A. M., Keeley, E. C., Lipson, L. C., Gimple, L. W., & Ragosta, M. (2010). Coronary Angiography is a Better Predictor of Mortality Than Noninvasive Testing in Patients Evaluated for Renal Transplantation. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 76(6), 795-801. doi:10.1002/ccd.22656